Development and evaluation of film coated tablets of letrozole

Name: Development and evaluation of film coated tablets of letrozole
Brand: LAP LAMBERT Academic Publishing
Availability: OutOfStock
Rating: 5 (1 reviews)

By Upasana Sharma

0 - Default Title

Description

The study is an attempt towards developing a formulation of an anti-estrogen drug, which belongs to non-steroidal aromatase inhibitor and which has in-vitro dissolution profile similar to that of reference product. Our target is to develop a dosage form similar to reference product for generic drug application to abbreviated new drug application (ANDA). Immediate drug delivery is required to alter the pharmacokinetics and pharmacodynamics of pharmacological active moieties by using physiological parameters inherent in the selected route of administration. It is also desirable to show rapid onset of action. In case of patient needing a quick action, conventional tablets are unable to release medicament rapidly. The drugs having long half-life and more bioavailability are beneficial for the formulation of immediate release dosage forms. Therefore, the present project involves the development of a formula for an orally administrable immediate release tablet of an anti-estrogen drug, letrozole which must be stable, bio-equivalent to reference listed drug product and has a reproducible and robust process of medication to prevent breast cancer relapse.

Product details

Binding:: Paperback
Number of Pages:: 124
Release Date:: 2025-07-07
Publication Date:: 2025-07-07
Publisher:: LAP LAMBERT Academic Publishing
Languages:: Original: English
ISBN10:: 6207459709
ISBN13:: 9786207459704
GPSR Manufacturer Reference:: [email protected]
Weight:: 203 g
Height:: 150 cm
Width:: 220 cm
Thickness:: 8 cm

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