Biomarkers of Neurodegenerative Disorders

Name: Biomarkers of Neurodegenerative Disorders
Brand: Springer Nature Switzerland
Availability: OutOfStock
Rating: 5 (1 reviews)

By Rawan Tarawneh

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Description

This book presents state-of-the-art knowledge regarding fluid and imaging biomarkers of neurodegenerative disorders, including Alzheimer disease and related dementias (ADRD). A cadre of the top experts in the field discuss the diagnostic and prognostic value of established and emerging biomarkers in ADRD, their ability to track or monitor disease progression or predict cognitive outcomes, and their potential as novel therapeutic targets. Biomarkers are discussed both in the context of specific disease mechanisms, including amyloid, tau, and synuclein pathologies, endothelial, vascular, neuronal, and synaptic injury, and glial reactivity as well as a wide spectrum of neurodegenerative disorders that encompass various pathologies. Multi-omics approaches in ADRD biomarker and drug target discovery including proteomics, genomics, and transcriptomics are covered. Importantly, the authors highlight the need to integrate biomarkers into various stages of ADRD drug development to accelerate drug discovery and approval. The book provides in-depth insight regarding significant progress in ADRD biomarker research over the last decade, addresses potential challenges in the translation of ADRD biomarkers into the clinic, and proposes important directions for future research.

Product details

Number of Pages:: 652
Release Date:: 2025-07-02
Publication Date:: 2025-07-02
Publisher:: Springer Nature Switzerland
Languages:: Original: English
ISBN10:: 3031808487
ISBN13:: 9783031808487
GPSR Manufacturer Reference:: [email protected]
Weight:: 1131 g
Height:: 160 cm
Width:: 241 cm
Thickness:: 41 cm

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