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Advances in NMR improve precision, sensitivity, and pharma application

By R. Vidhyalakshmi

Advances in NMR improve precision, sensitivity, and pharma application Mathematics

Advances in NMR improve precision, sensitivity, and pharma application

0 - Default Title
Description
Advances in Nuclear Magnetic Resonance (NMR) spectroscopy have revolutionized pharmaceutical analysis by offering enhanced precision, sensitivity, and broader applications in drug research and development. Modern NMR instruments equipped with high-field magnets, cryoprobes, and multidimensional techniques allow researchers to study complex molecular structures with remarkable clarity. These improvements help in identifying active pharmaceutical ingredients (APIs), detecting impurities, and characterizing polymorphic forms that can affect drug stability and efficacy. NMR also enables in-depth analysis of drug-protein and drug-receptor interactions, providing valuable insights into mechanisms of action and bioavailability. Non-destructive and highly reproducible, it serves as a reliable tool for quality control, metabolomics, and pharmacokinetics. Recent advances, such as solid-state NMR and in-cell NMR, have expanded its scope from small molecules to biologics, including proteins, peptides, and nucleic acids. With automation, improved sensitivity, and integration with computational methods, NMR spectroscopy continues to play a vital role in ensuring safe, effective, and innovative.
Product details
Binding:
Paperback
Number of Pages:
60
Release Date:
2025-09-29
Publication Date:
2025-09-29
Publisher:
LAP LAMBERT Academic Publishing
Languages:
Original: English
ISBN10:
6209048137
ISBN13:
9786209048135
GPSR Manufacturer Reference:
[email protected]
Weight:
107 g
Height:
150 cm
Width:
220 cm
Thickness:
4 cm
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