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Parkinson's Disease, Second Edition

By Serge Przedborski

Parkinson's Disease, Second Edition

By Serge Przedborski

0 - Default Title
Description
Parkinson's disease presents one of the most intricate challenges in neuroscience-a complex disorder with diverse motor and nonmotor symptoms, multifactorial causes, and enigmatic progression patterns. This volume, a thoroughly revised second edition, offers a comprehensive yet accessible synthesis of the clinical and biological foundations of Parkinson's disease, written explicitly to bridge the gap between clinicians and basic scientists.Parkinson's Disease, Second Edition brings together leading experts to provide an integrated view of the disorder's pathobiology, diagnosis, and emerging therapeutic strategies. It provides both historical context and an understanding of the clinical spectrum, as well as cutting-edge insights into genetics, biomarkers, the gut-brain axis, immune contributions, and neurodegenerative mechanisms.Highlights include:Up-to-date coverage of disease progression, cell-based therapies, and lipid dysregulationDeep dives into ¿-synuclein, LRRK2, and the genetic architecture of familial and sporadic PDExamination of neural circuit dysfunction and imaging correlates of symptomatologyNew frontiers in modeling, from rodent to primate and toxin to genetic paradigmsExplorations of mitochondria, autophagy, and neuroimmune interactions as pathogenic drivers
Intended for neurologists, neuroscientists, molecular biologists, and translational researchers, this book is a guide to entering and contributing to the field of Parkinson's disease research. For readers in both the clinic and the laboratory, it offers foundational knowledge and an integrative perspective in this rapidly evolving field.
Product details
Edition:
2
Number of Pages:
474
Release Date:
2025-02-25
Publication Date:
2025-09-01
Publisher:
Cold Spring Harbor Laboratory Press
Languages:
Original: English
ISBN10:
1621825035
ISBN13:
9781621825036
GPSR Manufacturer Reference:
[email protected]
Weight:
1079 g
Height:
183 cm
Width:
260 cm
Thickness:
30 cm
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