A brief review on synthesis of 2 & 6-substitutedquinazolin-4(3H)-ones

Name: A brief review on synthesis of 2 & 6-substitutedquinazolin-4(3H)-ones
Brand: LAP LAMBERT Academic Publishing
Availability: OutOfStock
Rating: 5 (1 reviews)

By Shankaraiah Pagilla

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Description

A comprehensive review was conducted on the significance of 6-substituted quinazolin-4(3H)-ones and 2-substituted phenyl quinazolin-4(3H)-ones in medicinal and polymer chemistry, as well as the synthetic methodologies reported in the literature up to March 2016. The primary objective of our current investigation is to expand the chemical space of quinazolin-4(3H)-ones by introducing a series of biologically active molecules, specifically those featuring 6-aryl/heteroaryl or quinoxalinyl groups, as well as 6-functionalized acyclic substituents on the quinazolinone core. Additionally, we aim to design and synthesize hybrid molecules incorporating both quinazolinone and triazole scaffolds via dipolar cycloaddition reactions. Our synthetic strategy also extensively explores the application of Kumada coupling, Castro-Stephens coupling, and multicomponent reactions.

Product details

Binding:: Paperback
Number of Pages:: 208
Release Date:: 2025-06-04
Publication Date:: 2025-06-04
Publisher:: LAP LAMBERT Academic Publishing
Languages:: Original: English
ISBN10:: 6206144836
ISBN13:: 9786206144830
GPSR Manufacturer Reference:: [email protected]
Weight:: 328 g
Height:: 150 cm
Width:: 220 cm
Thickness:: 13 cm

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