Phosphorylation profiling of systemin versus MAMP signaling reveals signaling specificity in plant immunity

Name: Phosphorylation profiling of systemin versus MAMP signaling reveals signaling specificity in plant immunity
Brand: Cuvillier
Availability: OutOfStock
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By Rong Li

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Description

Plasma membrane-localized pattern recognition receptors (PRRs) detect both microbe-associated molecular patterns (MAMPs) such as flg22 and chitin, and host-derived signals like systemin. While early signaling events (phosphorylation, ROS burst, MAPK activation) are largely similar, they lead to different biological outcomes:¿ MAMPs activate innate immunity,¿ Systemin induces wound and herbivore defense responses.To investigate how specificity arises, phospho-proteomics was applied in tomato cells (wild type vs. systemin receptor-deficient). In total, 4701 phospho-sites on 2119 proteins were identified. Using imputation and clustering, seven temporal phosphorylation patterns were observed:¿ Systemin uniquely caused dephosphorylation at 1-15 min,¿ flg22 triggered an early rapid phosphorylation response,¿ Chitin mainly induced late phosphorylation events.Specificity was illustrated by three protein groups:1. RLCK/PBL kinases ¿ different family members respond in an elicitor-specific way.2. S-type anion channel SLAC1 ¿ carries a single regulatory site, differentially phosphorylated depending on the elicitor.3. Phosphatase PLL1a ¿ has multiple elicitor-specific phospho-sites (flg22: Ser50-59, chitin: Ser86-89, systemin: Ser163-181).Network analysis suggested that PLL1a regulates RBOHs, which was functionally validated using phospho-mimic/dead PLL1 mutants in Nicotiana.

Product details

Binding:: Paperback
Edition:: 1
Number of Pages:: 144
Release Date:: 2025-08-06
Publication Date:: 2025-08-06
Publisher:: Cuvillier
Languages:: Original: English
ISBN10:: 3689523117
ISBN13:: 9783689523114
GPSR Manufacturer Reference:: [email protected]
Weight:: 197 g
Height:: 148 cm
Width:: 210 cm
Thickness:: 8 cm

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