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Fibrosis Research

By John Varga

Product Image: Fibrosis Research

Fibrosis Research

By John Varga

0 - Default Title
Description
Leading investigators review the highlights of current fibrosis research and the experimental methodologies used uncover the mechanisms that drive it. In their discussion of research methodologies utilizing cultured cells to model various aspects of the fibrotic response in vitro, the authors describe the isolation, characterization, and propagation of mesenchymal cells, and highlight the similarities and differences between methods that are appropriate for different types of fibroblasts. Approaches for studying collagen gene regulation and TGF-b production are also discussed, along with experimental methodologies utilizing animal models to study the pathogenesis of fibrosis. The protocols follow the successful Methods in Molecular Medicine¿ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Product details
Edition:
1
Number of Pages:
412
Release Date:
2005-08-08
Publication Date:
2005-08-08
Publisher:
Humana Press
Languages:
Original: English
ISBN10:
158829479X
ISBN13:
9781588294791
GPSR Manufacturer Reference:
[email protected]
Weight:
857 g
Height:
160 cm
Width:
241 cm
Thickness:
30 cm
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