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Self-Assembled Molecules - New Kind of Protein Ligands

By Irena Roterman

Self-Assembled Molecules - New Kind of Protein Ligands Medicine

Self-Assembled Molecules - New Kind of Protein Ligands

0 - Default Title
Description
The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but ¿naturally irreversible¿ complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book. This book is an open access under a CC BY license.
Product details
Binding:
Paperback
Edition:
1
Number of Pages:
152
Release Date:
2018-09-11
Publication Date:
2018-09-11
Publisher:
Springer International Publishing
Languages:
Original: English
ISBN10:
3319880713
ISBN13:
9783319880716
GPSR Manufacturer Reference:
[email protected]
Weight:
274 g
Height:
155 cm
Width:
235 cm
Thickness:
9 cm
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