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Protein Quality Control in Neurodegenerative Diseases

By Morimoto, Richard I.

Protein Quality Control in Neurodegenerative Diseases

By Morimoto, Richard I.

0 - Default Title
Description
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
Product details
Edition:
1
Number of Pages:
148
Release Date:
2012-12-12
Publication Date:
2012-12-12
Publisher:
Springer Berlin Heidelberg
Languages:
Original: English
ISBN10:
3642279279
ISBN13:
9783642279270
GPSR Manufacturer Reference:
[email protected]
Weight:
395 g
Height:
160 cm
Width:
241 cm
Thickness:
13 cm
Preview Link:
http://www.blickinsbuch.de/viewer/cm/access.php?djMxNTY9NDIwMzQ1MjgxNyZ2NzM3Nj05NzgzNjQyMjc5Mjcw
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