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HYPOPHOSPHATEMIC OSTEOMALACIA

By Zouhour Gassara

HYPOPHOSPHATEMIC OSTEOMALACIA

By Zouhour Gassara

- Default Title
Description
Diabetes phosphorus (DP) is a group of rare conditions characterized by renal phosphate leakage, leading to hypophosphatemia and osteomalacia. Although PD-related osteomalacia is much rarer than vitamin D-related osteomalacia, its etiologies are many and varied, including genetic, oncogenic and drug-related causes, as well as tubulopathies. The diagnosis of PD is primarily a biological one, based on hypophosphatemia associated with a low rate of tubular phosphorus reabsorption (TRP). Once the diagnosis has been made, a thorough etiological work-up is required to identify the underlying cause, plan treatment and prevent bone complications. This is based on biology, metabolic imaging and, if necessary, a genetic study. The main objective is to find a curable etiology, in particular an FGF-23-secreting tumour requiring surgical removal. In the absence of an identified cause, PD is said to be idiopathic. Its management is medical, based mainly on optimal phosphorus and calcitriol supplementation.
Product details
Binding:
Paperback
Number of Pages:
52
Release Date:
2025-08-29
Publication Date:
2025-08-29
Publisher:
Our Knowledge Publishing
Languages:
Original: English
ISBN10:
6208486297
ISBN13:
9786208486297
Weight:
96 g
Height:
150 cm
Width:
220 cm
Thickness:
4 cm
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