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Cellular Metamorphosis in Oral Carcinoma

By G. Gnananandar

Cellular Metamorphosis in Oral Carcinoma Medicine

Cellular Metamorphosis in Oral Carcinoma

0 - Default Title
Description
This book examines oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC) using histomorphometric analysis. It compares nuclear-to-cytoplasmic (N:C) ratios in cases of severe dysplasia and OSCC, and correlates the findings with Bryne's invasive tumor front grading system. Based on the analysis of 80 archival tissue samples using ProgRes software, the study reveals a progressive increase in nuclear abnormalities from dysplasia to carcinoma, with the highest N:C ratios observed in moderately differentiated OSCC. Statistical analysis confirms significant differences between groups, demonstrating that quantitative morphometry enhances diagnostic objectivity compared to subjective histological grading. The findings suggest that combining Bryne's criteria with N:C ratio measurements may improve the prediction of tumor behavior, particularly at the invasive front, thereby offering clinicians better tools for prognosis and treatment planning in oral precancer and cancer management.
Product details
Binding:
Paperback
Number of Pages:
56
Release Date:
2025-05-15
Publication Date:
2025-05-15
Publisher:
LAP LAMBERT Academic Publishing
Languages:
Original: English
ISBN10:
6208445728
ISBN13:
9786208445720
GPSR Manufacturer Reference:
[email protected]
Weight:
102 g
Height:
150 cm
Width:
220 cm
Thickness:
4 cm
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