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Molecular Epidemiology for Infectious Diseases
By Nigel Field
0 - Default Title
Description
This book bridges the gap between primary research and advanced graduate textbooks.
The field of molecular epidemiology has developed at the interface between epidemiology and molecular biology as high throughput molecular techniques have become cheaper and increasingly sophisticated for typing pathogen strains and characterising the host immune response. At the same time, bioinformatics and statistical methods have evolved so these complex and high-dimensional data can be analysed in combination with classical epidemiological data on time, person, and place. However, the analysis of datasets combining classical epidemiological and molecular data is highly specialised. Few postgraduate courses cover this topic in sufficient detail to allow meaningful interpretation.
This textbook introduces the major methods used to generate molecular datasets and the epidemiological and statistical concepts that are used to link these data with clinical and behavioural data. An introductory chapter explains key terms, definitions and the challenges of accurate and reproducible measurements in microbiology (metrology) and reviews the development of molecular epidemiology as a field and its history. Subsequent chapters introduce the readers to pathogen phylogenetics, host transcriptomics, proteomics, serology, and the microbiome. An additional chapter covers the ethical issues that arise when using molecular data combined with epidemiological and clinical information. The concluding chapter takes a look at the bigger picture and considers the contributions of molecular epidemiology to infectious disease control and health policy.
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Product details
Edition:
1
Number of Pages:
240
Release Date:
2025-09-27
Publication Date:
2025-09-27
Publisher:
Springer
Languages:
Original:
English
ISBN10:
3031764471
ISBN13:
9783031764479
GPSR Manufacturer Reference:
Weight:
571 g
Height:
160 cm
Width:
241 cm
Thickness:
18 cm
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