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Acute and Chronic Heart Failure

By Serafino Fazio

Acute and Chronic Heart Failure

By Serafino Fazio

0 - Default Title
Description
The topic "Acute and Chronic Heart Failure: Pathophysiology and New Therapeutic Developments" was chosen because, despite the progress made in recent decades in the prevention and treatment of cardiovascular diseases, they remain the leading cause of death in both developed and developing countries, and heart failure (HF) is, in any case, the endpoint of the majority of cardiac pathologies. HF prevalence is progressively increasing worldwide, with HF with preserved ejection fraction (HFpEF) now exceeding 50% prevalence in HF cases. The published contributions are numerous and all are interesting. I would, however, like to emphasize the fact that a rapidly growing condition worldwide-insulin resistance with associated hyperinsulinemia-that is present in a large proportion of HF patients, particularly in HF patients with preserved or only slightly reduced ejection fraction, is still not treated as an independent risk factor, despite the large body of the literature demonstrating its role in numerous significant metabolic and cardiovascular abnormalities. Patients with insulin resistance, which will later progress to type 2 diabetes, may, over time, develop pathological remodeling of the left ventricle with, initially, diastolic dysfunction and, subsequently, also systolic dysfunction, which will lead to the development of HF.
Product details
Number of Pages:
128
Release Date:
2025-10-06
Publication Date:
2025-10-06
Publisher:
MDPI AG
Languages:
Original: English
ISBN10:
3725852316
ISBN13:
9783725852314
Weight:
520 g
Height:
175 cm
Width:
250 cm
Thickness:
13 cm
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