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P38 Signaling Pathway

By Ezquerro, Juan José Sanz

Product Image: P38 Signaling Pathway

P38 Signaling Pathway

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Description
p38 Mitogen activated protein kinases (p38MAPK) are a highly evolutionary conserved group of protein kinases, which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration, and tumour formation. p38¿ is the best characterized, whereas the functions of p38ß, p38¿ and p38¿ have been less studied. The four p38MAPKs are ubiquitously expressed, although the level of expression of each isoform varies in particular tissues. Moreover, it is becoming clear that apart from common functions as stress kinases, they perform specific roles in a cell- and tissue-dependent manner, unveiling important functions in physiology and pathology. In this issue we provide an updated view of the p38 signalling pathway, including new regulatory mechanisms, substrates and implication in different diseases. This issue will be of interest to basic researchers working in cell signalling and immunology, to chemical biologists interested in drug discovery and also to clinicians interested in cell signalling pathways
Product details
Number of Pages:
194
Release Date:
2021-06-24
Publication Date:
2021-06-24
Publisher:
MDPI AG
Languages:
Original: English
ISBN10:
3036508589
ISBN13:
9783036508580
GPSR Manufacturer Reference:
[email protected]
Weight:
685 g
Height:
175 cm
Width:
250 cm
Thickness:
17 cm
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