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Exon Skipping and Inclusion Therapies

Exon Skipping and Inclusion Therapies

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Description
This fully updated edition presents a collection of protocols reflecting the latest advancements in exon skipping and inclusion strategies. The book explores the design of antisense oligonucleotide therapies, in vitro and in vivo evaluation of exon skipping in Duchenne muscular dystrophy, enhancing exon skipping efficiency, as well as methods involving spinal muscular atrophy and other diseases. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, Exon Skipping and Inclusion Therapies: Methods and Protocols, Second Edition serves as a valuable resource for scientists working to refine RNA-targeted therapeutics and translate them into clinical applications.
Product details
Edition:
2
Number of Pages:
520
Release Date:
2025-07-29
Publication Date:
2025-07-29
Publisher:
Springer
Languages:
Original: English
ISBN10:
1071647296
ISBN13:
9781071647295
GPSR Manufacturer Reference:
Weight:
1163 g
Height:
183 cm
Width:
260 cm
Thickness:
34 cm
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