Aceclofenac Loaded Nano Carriers: Production & Selection of Excipient

Name: Aceclofenac Loaded Nano Carriers: Production & Selection of Excipient
Brand: LAP LAMBERT Academic Publishing
Availability: OutOfStock
Rating: 5 (1 reviews)

By Patel, Dilip K

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Description

This book chapter explores the formulation, production, and excipient compatibility of nanostructured lipid carriers (NLCs) for the topical delivery of aceclofenac. It emphasizes the selection and optimization of lipids and surfactants to enhance drug loading, stability, and skin penetration. Special emphasis is placed on the selection of lipid excipients, such as glyceryl monostearate, stearic acid, and oleic acid, and stabilizers like Poloxamer 188 or Tween 80, which significantly influence particle size, zeta potential, drug entrapment, and release kinetics. Various production methods including high-pressure homogenization and ultrasonication are discussed with respect to scalability, reproducibility, and stability. The chapter highlights the advantages of NLC-based systems in achieving sustained release, improved bioavailability, and reduced systemic side effects, offering valuable insights for advanced topical formulations.

Product details

Binding:: Paperback
Number of Pages:: 76
Release Date:: 2025-11-07
Publication Date:: 2025-11-07
Publisher:: LAP LAMBERT Academic Publishing
Languages:: Original: English
ISBN10:: 6209231225
ISBN13:: 9786209231223
Weight:: 131 g
Height:: 15 cm
Width:: 22 cm
Thickness:: 0.5 cm

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