Genome mining and metabolic engineering of Aureobasidium pullulans NRRL 62031 for enhanced polymalate production

Name: Genome mining and metabolic engineering of Aureobasidium pullulans NRRL 62031 for enhanced polymalate production
Brand: Apprimus Verlag
Availability: OutOfStock
Rating: 5 (1 reviews)

By Difan Xiao

0 - Default Title

Description

Polymalate (PMA), a promising drug delivery system, can be produced by Aureobasidium pullulans NRRL 62031. The key genetic determinant for PMA polymerization and the primary pathway for malate synthesis were identified. Four gene knockout targets and one overexpression target were found to enhance PMA titer. Genetic insights into PMA hydrolysis were also obtained through bioinformatics. This study lays the foundation for the large-scale production of PMA and its medical applications.

Product details

Binding:

Paperback

Edition:

1

Number of Pages:

232

Release Date:

2025-06-24

Publication Date:

2025-06-24

Publisher:

Apprimus Verlag

Languages:

Original: English

ISBN10:

3985552886

ISBN13:

9783985552887

GPSR Manufacturer Reference:

[email protected]

Weight:

342 g

Height:

148 cm

Width:

210 cm

Thickness:

15 cm

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