Anticarcinogenic activity of Clerodendrum serratum in albino mice

Name: Anticarcinogenic activity of Clerodendrum serratum in albino mice
Brand: LAP LAMBERT Academic Publishing
Availability: OutOfStock
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By Jayaraj Chinchali

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Description

Skin, a major environmental interface for the body, is accidentally or occupationally exposed to a number of chemical mutagens and carcinogens. Skin cancer accounts for 30% of all diagnosed cancers in the world. The evaluation of anticarcinogenic activity of Clerodendrum serratum leaf extract on DMBA induced skin carcinogenesis in swiss albino mice revealed that there was decrease in the body and organs weight, affected biochemical contents, dehydrogenases and phosphatases activities and oxidative stress parameters of liver, kidney and testes of mice. Amelioration in the above mentioned parameters was observed on treatment with methanolic leaf extract of Clerodendrum serratum, indicating its anticarcinogenic potential. The inferences drawn from the study revealed that the methanolic leaf extract of Clerodendrum serratum recovered the biochemical contents, dehydrogenases and phosphatases activity and oxidative stress parameters of liver, kidney and testes of mice. The presence of major chemical components such as phenolics, steroids, diterpenes and triterpenes, flavonoids and volatile oils attributed its chemopreventive potential as an antioxidant and antiproliferative agent........

Product details

Binding:: Paperback
Number of Pages:: 152
Release Date:: 2014-11-20
Publication Date:: 2014-11-20
Publisher:: LAP LAMBERT Academic Publishing
Languages:: Original: English
ISBN10:: 3659640859
ISBN13:: 9783659640858
Weight:: 244 g
Height:: 150 cm
Width:: 220 cm
Thickness:: 10 cm

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