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Drug Metabolism

By Caira, Mino R

Drug Metabolism Medicine

Drug Metabolism

By Caira, Mino R

0 - Default Title
Description
Drug Metabolism: Current Concepts Corina Ionescu and Mino R Caira Drug Metabolism: Current Concepts provides a comprehensive understanding of the processes that take place following ingestion of a medicinal agent or xenobiotic, with an emphasis on the crucial role of metabolism (biotransformation). How a sound knowledge of these phenomena is incorporated into the design of effective new drug candidates is also explained. The user-friendly text focuses on concepts rather than extraneous details and is supported by many illustrated examples of biotransformations as well as frequent references to current critical reviews and articles highlighting the nature of research objectives in this vibrant area of medicinal development. The final topic on strategies for drug design relies on the background provided by the rest of the book.
The book includes chapters on ADME (drug absorption, distribution, metabolism and elimination)
Pathways of biotransformation (Phase I and Phase II metabolic reactions)
Enzymatic systems involved in biotransformation
Induction and inhibition of drug-metabolising enzymes
Factors that influence drug biotransformation
The role of pharmacogenetics
Drug-drug interactions and adverse reactions
Strategies for drug design. This book is ideally suited as an advanced text for courses in drug metabolism for students of medicine, pharmacy, pharmacology, biochemistry; and for courses in drug design and drug delivery for students of medicinal chemistry. It is also appropriate for professional seminars or courses that relate to the fate of a drug in the body, drug interactions, adverse reactions and drug design.
Product details
Edition:
1
Number of Pages:
422
Release Date:
2006-02-28
Publication Date:
2006-02-28
Publisher:
Springer
Languages:
Original: English
ISBN10:
1402041411
ISBN13:
9781402041419
GPSR Manufacturer Reference:
[email protected]
Weight:
918 g
Height:
169 cm
Width:
246 cm
Thickness:
24 cm
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