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Neoadjuvant treatment of rectal cancer

By Dhouha Bacha

Neoadjuvant treatment of rectal cancer

By Dhouha Bacha

0 - Default Title
Description
Objective: The aim of this work was to study the predictive factors of HR to neoadjuvant treatment of locally advanced CR in Tunisian patients.Methods: Retrospective study of patients with CR operated after neoadjuvant radiochemotherapy (RCT). HR was assessed according to Dworak's TRG, whose five grades were subsequently grouped into two categories: Response Group (R) for TRG3 and 4 and No Response Group (PR) for TRG 0, 1 and 2.Results: The study included 88 patients with a mean age of 60 years. The site of CR was the middle rectum in 63% of cases. Node invasion was noted in 52 patients (59%). The R group comprised 29 patients (33%) and the PR group 59 patients (67%). In multivariate analysis, predictive factors for HR were age ¿ 60 years, male gender and pre-therapeutic parietal infiltration of cT3.Conclusion: In locally advanced RC, patients aged ¿ 60 years, male gender, with pre-therapeutic cT3 parietal infiltration, would be the best candidates for a strategy of neoadjuvant RCT followed by surgical excision.
Product details
Binding:
Paperback
Number of Pages:
64
Release Date:
2025-08-29
Publication Date:
2025-08-29
Publisher:
Our Knowledge Publishing
Languages:
Original: English
ISBN10:
6208496578
ISBN13:
9786208496579
GPSR Manufacturer Reference:
[email protected]
Weight:
113 g
Height:
150 cm
Width:
220 cm
Thickness:
4 cm
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