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Paediatric Formulation

Paediatric Formulation Natural Sciences

Paediatric Formulation

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Description
The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.
Product details
Number of Pages:
206
Release Date:
2021-06-17
Publication Date:
2021-06-17
Publisher:
MDPI AG
Languages:
Original: English
ISBN10:
303650740X
ISBN13:
9783036507408
GPSR Manufacturer Reference:
Weight:
715 g
Height:
175 cm
Width:
250 cm
Thickness:
18 cm
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