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Role of HER2 - From Molecular Mechanisms to Targeted Therapies

Role of HER2 - From Molecular Mechanisms to Targeted Therapies Medicine

Role of HER2 - From Molecular Mechanisms to Targeted Therapies

0 - Default Title
Description
This book explores the crucial role that Human Epidermal Growth Factor Receptor 2 (HER2) plays in the initiation and progression of cancer, as well as cutting-edge molecular mechanisms, precision medicine, and novel targeted treatments, including lapatinib, pertuzumab, and trastuzumab. HER2 overexpression, especially for breast cancer and beyond, in combination with other development therapies, antibody-drug conjugates, and overcomes resistance mechanisms. This book provides comprehensive coverage of the PI3K/AKT and MAPK signaling pathways, up-to-date information on next-generation HER2 inhibitors, including neratinib and tucatinib, and offers helpful advice for researchers and clinicians managing HER2-positive tumors. This book, which links laboratory findings with clinical applications and offers hope for better outcomes in HER2-driven cancers, is an essential resource for oncologists, molecular biologists, and pharmaceutical scientists. It does so clearly and understandably.
Product details
Number of Pages:
106
Release Date:
2025-11-26
Publication Date:
2025-11-26
Publisher:
IntechOpen
Languages:
Original: English
ISBN10:
1836344643
ISBN13:
9781836344643
GPSR Manufacturer Reference:
Weight:
435 g
Height:
183 cm
Width:
260 cm
Thickness:
12 cm
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