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Aberrant Phenotype in Malignant Lymphoma

By Alessandro D'Amuri

Product Image: Aberrant Phenotype in Malignant Lymphoma

Aberrant Phenotype in Malignant Lymphoma

By Alessandro D'Amuri

- Default Title
Description
Peripheral B- and T-cell lymphomas may express immune phenotypes which differ from those seen on normal peripheral B- and T-cells, so-called aberrant phenotypes that may consist of atypical cross-lineage antigen expression, asynchronous-antigen expression, antigen overexpression, tissue-restricted phenotypes, abnormal maturation pathways. In our studies we reported two different types of aberrant phenotypes in malignant lymphoma.The aberrant expression of B-and T-cell markers may be not incidental but could be indicative of antigenic phenotype that has not been recognized previously. These cases with aberrant phenotypes require genotypic analysis for lineage assignment and studies of such cases may be helpful to better elucidate whether they represent a distinct entity with clinical, immunophenotypic and molecular characteristics or just an incidental phenomenon during malignant transformation.
Product details
Binding:
Paperback
Number of Pages:
64
Release Date:
2012-10-18
Publication Date:
2012-10-18
Publisher:
LAP LAMBERT Academic Publishing
Languages:
Original: English
ISBN10:
3659267732
ISBN13:
9783659267734
GPSR Manufacturer Reference:
[email protected]
Weight:
113 g
Height:
150 cm
Width:
220 cm
Thickness:
4 cm
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