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Novel and Facile chromatography and spectrophotometry methods

By Mahmoud Abdelfatah

Novel and Facile chromatography and spectrophotometry methods

By Mahmoud Abdelfatah

0 - Default Title
Description
A novel, specific, simple, precise, accurate, stability-indicating RP-HPLC methods and different spectrophotometric methods as First derivative ratio, ratio difference and ratio subtracting methods are developed and validated for the determination of some pharmaceutical drugs produced by Hikma Company which are used in the treatment of seasonal and perennial allergic conjunctivitis, chronic hepatitis C (CHC) in adults and antibacterial. These drugs include Azelastine hydrochloride (AZH), Benzalkonium chloride (BAC), Sofosbuvir (SOF), Ledipasvir (LDV), Cefixime trihydrate (CFX) and Sodium benzoate (SDM) in pure and in pharmaceutical dosage forms. Surveying the literature dealing with the same technique with drugs similar to that under study, Checking the validity of the applied analytical method and achieving the optimum condition according to ICH. Study of the stability indicating method using stress condition to validate the method of analysis of the drugs under study. Finally, the obtained results for the proposed methods were statistically compared with the official methods using student's and F-ratio tests, showing that the two methods are accurate and precise.
Product details
Binding:
Paperback
Number of Pages:
240
Release Date:
2025-11-03
Publication Date:
2025-11-03
Publisher:
LAP LAMBERT Academic Publishing
Languages:
Original: English
ISBN10:
6209199941
ISBN13:
9786209199943
Weight:
375 g
Height:
150 cm
Width:
220 cm
Thickness:
15 cm
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