{"product_id":"kroger-nicolaus-selected-cd34-stem-cells-for-graft-engineering-9783131738813","title":"Selected CD34+ Stem Cells for Graft Engineering","description":"Engineering of stem cell grafts by selection of CD34+ cells has been used in\nautologous and allogeneic hematopoietic stem cell transplantation (HSCT)\nfor more than two decades.\nPrevention of severe GvHD in allogeneic HSCT is crucial to reduce the risk\nof transplant-related mortality and morbidity, and to maintain a high level\nof quality of life. One approach widely used in clinical practice to reduce\nincidences of GvHD is the ex vivo removal of T lymphocytes from the graft\nby selection of CD34+ cells. Moreover, immunoselected CD34+ cells are\nused to boost engraftment with low risk of developing GvHD in patients\nexhibiting poor graft function. In autologous HSCT, this method of ex vivo\ngraft manipulation may prevent reinfusion of tumor cells and diseasecausing\nlymphocytes.\nThirty-four compelling case reports are presented in this book, in which\nthis powerful technology was used in multiple stem cell transplantation\nsettings.","brand":"Thieme","offers":[{"title":"Default Title","offer_id":53663167775062,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0925\/5829\/5382\/files\/product_image_9783131738813_1.jpg?v=1778780976","url":"https:\/\/www.momoxbooks.com\/products\/kroger-nicolaus-selected-cd34-stem-cells-for-graft-engineering-9783131738813","provider":"momoxbooks","version":"1.0","type":"link"}