{"product_id":"kouira-mouna-place-of-surgery-in-early-stage-iv-breast-cancer-9786209373527","title":"Place of surgery in early stage IV breast cancer","description":"Early metastatic breast cancer is an aggressive disease. We carried out a retrospective study of 221 cases of stage IV breast cancer to assess the value of local surgery in metastatic breast cancer. One hundred and twenty-nine patients underwent surgery. Healthy margins were obtained in 76.1% of cases. Operated patients had a less advanced T stage (p=0.0001), fewer visceral metastases (p=0.0001) and fewer secondary lesions (p=0.001). After a median follow-up of 36 months, overall survival at 1, 3 and 5 years was better in the operated group (p=0.0001, p=0.002, p=0.019). In the case of isolated bone metastases, operated patients had better overall survival at 1, 3 and 5 years than non-operated patients (p=0.02, p=0.037, p=0.033). Surgical technique had no impact on overall survival or local recurrence. In sano surgery improved 5-year OS (p=0.047). In multivariate analysis, the factors influencing surgical outcome were the presence of visceral metastases, more than 3 metastases and tumour resection limits.","brand":"Our Knowledge Publishing","offers":[{"title":"Default Title","offer_id":53815982195030,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0925\/5829\/5382\/files\/product_image_9786209373527_1_1c8eb1d4-9bb1-450e-8bcd-0e4e8e9e0b1a.jpg?v=1783405703","url":"https:\/\/www.momoxbooks.com\/products\/kouira-mouna-place-of-surgery-in-early-stage-iv-breast-cancer-9786209373527","provider":"momoxbooks","version":"1.0","type":"link"}