{"product_id":"gassara-zouhour-hypophosphatemic-osteomalacia-9786208486297","title":"HYPOPHOSPHATEMIC OSTEOMALACIA","description":"Diabetes phosphorus (DP) is a group of rare conditions characterized by renal phosphate leakage, leading to hypophosphatemia and osteomalacia. Although PD-related osteomalacia is much rarer than vitamin D-related osteomalacia, its etiologies are many and varied, including genetic, oncogenic and drug-related causes, as well as tubulopathies. The diagnosis of PD is primarily a biological one, based on hypophosphatemia associated with a low rate of tubular phosphorus reabsorption (TRP). Once the diagnosis has been made, a thorough etiological work-up is required to identify the underlying cause, plan treatment and prevent bone complications. This is based on biology, metabolic imaging and, if necessary, a genetic study. The main objective is to find a curable etiology, in particular an FGF-23-secreting tumour requiring surgical removal. In the absence of an identified cause, PD is said to be idiopathic. Its management is medical, based mainly on optimal phosphorus and calcitriol supplementation.","brand":"Our Knowledge Publishing","offers":[{"title":"Default Title","offer_id":53736117010774,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":false}],"url":"https:\/\/www.momoxbooks.com\/products\/gassara-zouhour-hypophosphatemic-osteomalacia-9786208486297","provider":"momoxbooks","version":"1.0","type":"link"}