{"product_id":"ariens-e-j-drug-design-medicinal-chemistry-a-series-of-monographs-vol-2-9781483202617","title":"Drug Design: Medicinal Chemistry: A Series of Monographs, Vol. 2","description":"Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design of organophosphate and carbamate inhibitors of cholinesterases. The text also describes the design of reactivators for irreversibly blocked acetylcholinesterase; drug design based on the inhibition of protein synthesis in the context of susceptible enzymic reactions; as well as the role of enzymes and their synthesis as a target for antibiotic action. The rational design of antiviral agents; the design of penicillin; the design of peptide hormone analogs; as well as the advances in the design of diuretics are also considered. The book further tackles the design of biologically active steroids; the rational elements in the development of superior neuromuscular blocking agents; and the design of tumor-inhibitory alkylating drugs. Pharmacologists, chemists, and people involved in drug design will find the book invaluable.","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":53703243268438,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0925\/5829\/5382\/files\/product_image_9781483202617_1.jpg?v=1781758703","url":"https:\/\/www.momoxbooks.com\/products\/ariens-e-j-drug-design-medicinal-chemistry-a-series-of-monographs-vol-2-9781483202617","provider":"momoxbooks","version":"1.0","type":"link"}