{"product_id":"antonio-lopalco-paediatric-formulation-9783036507408","title":"Paediatric Formulation","description":"The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.","brand":"MDPI AG","offers":[{"title":"Used - good","offer_id":53281397670230,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0925\/5829\/5382\/files\/product_image_9783036507408_1_3bad2997-aaf2-4486-9467-ac50114caff4.jpg?v=1781223514","url":"https:\/\/www.momoxbooks.com\/products\/antonio-lopalco-paediatric-formulation-9783036507408","provider":"momoxbooks","version":"1.0","type":"link"}