{"product_id":"ammara-riaz-role-of-her2-from-molecular-mechanisms-to-targeted-therapies-9781836344643","title":"Role of HER2 - From Molecular Mechanisms to Targeted Therapies","description":"This book explores the crucial role that Human Epidermal Growth Factor Receptor 2 (HER2) plays in the initiation and progression of cancer, as well as cutting-edge molecular mechanisms, precision medicine, and novel targeted treatments, including lapatinib, pertuzumab, and trastuzumab. HER2 overexpression, especially for breast cancer and beyond, in combination with other development therapies, antibody-drug conjugates, and overcomes resistance mechanisms. This book provides comprehensive coverage of the PI3K\/AKT and MAPK signaling pathways, up-to-date information on next-generation HER2 inhibitors, including neratinib and tucatinib, and offers helpful advice for researchers and clinicians managing HER2-positive tumors. This book, which links laboratory findings with clinical applications and offers hope for better outcomes in HER2-driven cancers, is an essential resource for oncologists, molecular biologists, and pharmaceutical scientists. It does so clearly and understandably.","brand":"IntechOpen","offers":[{"title":"Default Title","offer_id":53811652264278,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0925\/5829\/5382\/files\/product_image_9781836344643_1.jpg?v=1781817353","url":"https:\/\/www.momoxbooks.com\/products\/ammara-riaz-role-of-her2-from-molecular-mechanisms-to-targeted-therapies-9781836344643","provider":"momoxbooks","version":"1.0","type":"link"}